Clean hands. Soft skin. No alcohol.
Prefense foaming sanitizer helps reduce germs that may cause disease. Aloe and vitamin E keep your skin soft with every pump. Made in the USA.
Keep protection in your home, car, and bag. Bundles save you more than buying 1 bottle at a time. Orders of $49.99 or more ship for a flat $4.99.
Shop Bundle DealsPick the size that fits your day. Singles, refills, dispensers, and accessories.
Shop All SizesAlcohol-Free Formula
Prefense uses safe, skin-friendly formulas to help reduce germs that may cause disease on your hands.
Foaming, Non-Drying Application
Prefense applies as a moisturizing foam, gentle enough for frequent use.
Skin-Friendly
Water-based formula with no alcohol. Prefense helps your skin keep its natural moisture.
Save 15% on your first order
Join the Prefense list. We send a couple of emails a month with refill reminders and the occasional discount. Your code arrives the moment you sign up.
"As an RN, I never liked using the hand sanitizers as they would dry out my skin & smell of chemicals. Soap & water was always good enough for me...until I was introduced to Prefense."
Shawn-Kristin, RN
"I have been using Prefense for two years and travel almost every week. I really like the way my hands feel after applying. Not sticky or slimy like other hand sanitizers."
John C.
"I have been using Prefense over the past few months and have received very positive feedback from my patients. They like the fact that it is not a drying product and actually moisturizes their skin. My patients have a high level of confidence in this product."
Michael K. MD